Christopher Bare
Director, Cytometry and Cell Sorting Facility

BS (Biology – Genetics and Development), Cornell University College of Agriculture and Life Sciences, Ithaca, NY

Research Interest
Mr. Bare utilizes the fundamental concepts of flow cytometry in the detection, characterization, and separation of biological particles at both the cellular and subcellular domains. His research interests involve the development and refinement of commercial cell sorting instruments for fluorescent-tagged studies of extracellular vesicle (EV) populations in both normal and pathologic human cohorts. In addition, Mr. Bare is involved in the development of mechanisms to characterize and separate extracellular vesicles using label-free optical spectroscopy and multi-illumination spectral signature detection with potential for therapeutic applications. His research has taken two paths. The first is to assess EV diversity and signatures on current multilaser cytometers. The second is to develop detection hardware specific to the extracellular vesicle size range and coordinate physical phenomena such as Brillouin light scatter and the x-ray water window.

Selected Publications

  • Fullard JF, Giambartolomei C, Hauberg ME, Xu K, Voloudakis G, Shao Z, Bare C, Dudley JT, Mattheisen M, Robakis NK, Haroutunian V, Roussos P. Open chromatin profiling of human postmortem brain infers functional roles for non-coding schizophrenia loci. Hum Mol Genet. 2018 Jun 29; PubMed Central PMCID: PMC7530524.
  • Gobbi A, Stoddart CA, Locatelli G, Santoro F, Bare C, Linquist-Stepps V, Moreno ME, Abbey NW, Herndier BG, Malnati MS, McCune JM, Lusso P. Coinfection of SCID-hu Thy/Liv mice with human herpesvirus 6 and human immunodeficiency virus type 1. J Virol. 2000 Sep;74(18):8726-31. PubMed Central PMCID: PMC116384.
  • Berkowitz RD, van’t Wout AB, Kootstra NA, Moreno ME, Linquist-Stepps VD, Bare C, Stoddart CA, Schuitemaker H, McCune JM. R5 strains of human immunodeficiency virus type 1 from rapid progressors lacking X4 strains do not possess X4-type pathogenicity in human thymus. J Virol. 1999 Sep;73(9):7817-22. PubMed Central PMCID: PMC104310.


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