New Article Authored by Dr. Mala Rao and Members of the CDR

New York – Dr. Mala Rao and members of the Center for Dementia Research along with colleagues from NKI, published a new piece titled “Specific calpain inhibition by calpastatin prevents tauopathy and neurodegeneration and restores normal lifespan in Tau P301L mice.” The article which appears in the July issue of The Journal of Neuroscience, discusses findings that support the therapeutic promise of highly specific calpain inhibition in the treatment of tauopathies and other neurodegenerative states.

The mounting evidence pointing to calpains as a target in major neurodegenerative diseases should provide strong motivation to pursue further drug development to modulate the calpain–calpastatin system.