Science Advances Publishes New Research by the Nixon Lab

The April 28 edition of Sciences Advances features a new paper by  Pearl Lie and Nixon Lab researchers titled, Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca efflux and disrupted by PSEN1 loss of function.” This groundbreaking research defines a mechanism linking dysfunction and mistrafficking in lysosomal pathways to neuritic dystrophy under neurodegenerative conditions. Lab members Pearl P. Y. Lie (first author), Lang Yoo (co-first author), Chris N. Goulbourne, Martin J. Berg, Philip Stavrides, Chunfeng Huo, Ju-Hyun Lee, and Ralph A. Nixon are co-authors of the study.