Viable Microisolated Neurons from Postmortem Brain Tissues

In a recent study published in the Journal of Clinical Medicine, Melissa Alldred and Steven Ginsberg report that single-population RNA-seq analysis demonstrates that microisolated neurons from both postmortem human and mouse brain tissues are viable for transcriptomic profiling, including differential gene expression assessment and bioinformatic pathway inquiry. The article, titled “Microisolation of Spatially Characterized Single Populations of Neurons for RNA Sequencing from Mouse and Postmortem Human Brain Tissues,” was published in the May 5, 2023 edition.